Article
TNF-alpha -308 G>A and -238 G>A polymorphisms are not major risk factors in Caucasian patients with exfoliation glaucoma.
Molecular vision - 1 Jan 2009
Mossböck Georg, Renner Wilfried, El-Shabrawi Yosuf, Faschinger Christoph, Schmut Otto, Wedrich Andreas, Zimmermann Christina, Weger Martin
Abstract excerpt
PURPOSE: TNF-alpha has been suggested to participate in the pathogenesis of exfoliation glaucoma (XFG). The purpose of the present study was to investigate a hypothesized association between two common functional polymorphisms in the promoter region of the TNF-alpha gene (TNF-alpha -308 G>A, rs1800629, and TNF-alpha -238 G>A, rs361525) and the presence of XFG in a Caucasian population. METHODS: The present...
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