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Article

Theoretical study of the Usutu virus helicase 3D structure, by means of computer-aided homology modelling

25 Jun 2009

Abstract excerpt

BACKGROUND: Usutu virus belongs to the Flaviviridae viral family and constitutes an important pathogen. The viral helicase is an ideal target for inhibitor design, since this enzyme is essential for the survival, proliferation and transmission of the virus. RESULTS: Towards a drug-design approach, the 3D model of the Usutu virus helicase structure has been designed, using conventional homology modelling...

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PMID: 19555498
DOI: 10.1186/1742-4682-6-9

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