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Article

The influence of JNK and P38 MAPK inhibition on IL-12P40 and IL-23 production depending on IL12B promoter polymorphism.

Cellular & molecular biology letters - 1 Jan 2009

Dobreva Zlatka Georgieva, Stanilova Spaska Angelova, Miteva Lyuba Dineva

Abstract excerpt

The interleukin-12p40 gene (IL12B) encodes the p40 polypeptide chain, which, together with p19, composes IL-23. A bi-allelic promoter polymorphism (IL12Bpro) located at -2703 bp of the transcription initiation site has been reported to show associations with IL-12p40 production. To elucidate the...

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Source

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Identifiers

PMID: 19554267
DOI: 10.2478/s11658-009-0022-4
PMCID: PMC6275601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19554267-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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