Article
The combined effect of interleukin (IL)-10 and IL-12 polymorphisms on induced cytokine production.
Human immunology - 1 Sept 2008
Miteva Lyuba, Stanilova Spaska
Abstract excerpt
Interleukin (IL)-12 and IL-10 are immunoregulatory cytokines with an antagonistic effect of the T-helper (Th)1/Th2 cytokine balance and provide a functional link between innate and adaptive immune responses. The aim of the study was to investigate the combined effect of -1082A*G in IL10 and +16974A*C in IL12B single nucleotide polymorphisms (SNPs) on induced cytokine production by stimulated peripheral blood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
