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Article

Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Jun 2009

Abdallah Luna, Bonasera Stephen J, Hopf F Woodward, O'Dell Laura, Giorgetti Marco, Jongsma Minke, Carra Scott, Pierucci Massimo, Di Giovanni Giuseppe, Esposito Ennio, Parsons Loren H, Bonci Antonello, Tecott Laurence H

Abstract excerpt

The impact of serotonergic neurotransmission on brain dopaminergic pathways has substantial relevance to many neuropsychiatric disorders. A particularly prominent role has been ascribed to the inhibitory effects of serotonin 2C receptor (5-HT(2C)R) activation on physiology and behavior mediated by the mesolimbic dopaminergic pathway, particularly in the terminal region of the nucleus accumbens. The influence of...

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Identifiers

PMID: 19553455
DOI: 10.1523/JNEUROSCI.3905-08.2009
PMCID: PMC3077993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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