Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Palmitoylation of the Influenza A Virus M2 Protein Is Not Required for Virus Replication In Vitro but Contributes to Virus Virulence

25 Jun 2009

Abstract excerpt

The influenza A virus M2 protein has important roles during virus entry and in the assembly of infectious virus particles. The cytoplasmic tail of the protein can be palmitoylated at a cysteine residue, but this residue is not conserved in a number of human influenza A virus isolates. Recombinant viruses encoding M2 proteins with a serine substituted for the cysteine at position 50 were generated in the A/WSN/33...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza Virus Research Studies
Share to interferon and immune responses
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19553312
DOI: 10.1128/jvi.01129-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Palmitoylation of the Influenza A Virus M2 Protein Is Not Required for Virus Replication In Vitro but Contributes to Virus VirulencePMID 19553312Read ↗

Palmitoylation at Residue C221 of Japanese Encephalitis Virus NS2A Protein Contributes to Viral Replication Efficiency and VirulenceSemantic proximity Read ↗

Tyrosines in the influenza A virus M2 protein cytoplasmic tail are critical for production of infectious virus particles.Semantic proximity Read ↗

Transmembrane Domain Length of Influenza a Virus M2 Does Not Determine Its Non-Lipid Raft Localization.Semantic proximity Read ↗

Palmitoylation of SARS-CoV-2 Envelope protein is central to virus particle formation.Semantic proximity Read ↗

Palmitoylation of the hemagglutinin of influenza B virus by ER-localized DHHC enzymes 1, 2, 4, and 6 is required for efficient virus replication.Semantic proximity Read ↗

Mutations in the membrane-proximal region of the influenza A virus M2 protein cytoplasmic tail have modest effects on virus replication.Semantic proximity Read ↗

Mutations in the Influenza A Virus M1 Protein Enhance Virus Budding To Complement Lethal Mutations in the M2 Cytoplasmic Tail.Semantic proximity Read ↗

Influenza A virus can undergo multiple cycles of replication without M2 ion channel activity.Semantic proximity Read ↗

The infection of mammalian and insect cells with SFV bearing nsP1 palmitoylation mutationsSemantic proximity Read ↗

Palmitoylation of hepatitis C virus core protein is important for virion production.Semantic proximity Read ↗

Cytoplasmic domain of CM2 is involved in the replication of influenza C virus.Semantic proximity Read ↗

Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct EctodomainSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.