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Article

Not all DMT1 mutations lead to iron overload.

Blood cells, molecules & diseases - 1 Jan 2000

Blanco Esther, Kannengiesser Caroline, Grandchamp Bernard, Tasso María, Beaumont Carole

Abstract excerpt

DMT1 is a membrane-bound divalent metal transporter, which co-transports protons and (Fe(2+)) from an acidic microenvironment (endosome, duodenal lumen) to the cell cytosol. Results from animal models and from patients have shown that DMT1 is required for intestinal iron absorption and iron acquisition by erythrocytes. Only three human patients with DMT1 mutations have been described so far. They presented with...

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Identifiers

PMID: 19553145
DOI: 10.1016/j.bcmd.2009.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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