Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the gene encoding DMT1: clinical presentation and treatment.

Seminars in hematology - 1 Oct 2009

Iolascon Achille, De Falco Luigia

Abstract excerpt

Divalent metal transporter 1 (DMT1) is the protein that allows elemental iron entry into the duodenal cell. It is expressed ubiquitously and it also allows the iron exit from the endosomes. This protein plays a central role in iron metabolism and it is strictly regulated. Several animal models el...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia
Share to Cation Transport Proteins
Share to Erythropoiesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythropoietin

Share to Iron-Binding Proteins

Share to Iron Overload

Share to Up-Regulation

Source

Identifiers

PMID: 19786204
DOI: 10.1053/j.seminhematol.2009.06.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19786204-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the gene encoding DMT1: clinical presentation and treatment.PMID 19786204Read ↗

Not all DMT1 mutations lead to iron overload.Semantic proximity Read ↗

Two new human DMT1 gene mutations in a patient with microcytic anemia, low ferritinemia, and liver iron overload.Semantic proximity Read ↗

Microcytic anemia and hepatic iron overload in a child with compound heterozygous mutations in DMT1 (SCL11A2).Semantic proximity Read ↗

Divalent metal transporter 1.Semantic proximity Read ↗

Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload.Semantic proximity Read ↗

Natural history of recessive inheritance of DMT1 mutations.Semantic proximity Read ↗

A novel R416C mutation in human DMT1 (SLC11A2) displays pleiotropic effects on function and causes microcytic anemia and hepatic iron overloadSemantic proximity Read ↗

Rare anemias due to genetic iron metabolism defects.Semantic proximity Read ↗

H(+)-coupled divalent metal-ion transporter-1: functional properties, physiological roles and therapeutics.Semantic proximity Read ↗

A novel N491S mutation in the human SLC11A2 gene impairs protein trafficking and in association with the G212V mutation leads to microcytic anemia and liver iron overload.Semantic proximity Read ↗

Ferroportin disease: pathogenesis, diagnosis and treatment.Semantic proximity Read ↗

Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.