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Article

Protective KIR-HLA interactions for HCV infection in intravenous drug users.

Molecular immunology - 1 Aug 2009

Zúñiga Joaquín, Romero Viviana, Azocar José, Terreros Daniel, Vargas-Rojas María Inés, Torres-García Diana, Jiménez-Alvarez Luis, Vargas-Alarcón Gilberto, Granados-Montiel Julio, Husain Zaheed, Chung Raymond T, Alper Chester A, Yunis Edmond J

Abstract excerpt

Intravenous drug use has become the principal route of hepatitis C virus (HCV) transmission due to the sharing of infected needles. In this study, we analyzed the distribution of HLA-KIR genotypes among 160 Puerto Rican intravenous drug users (IDUs) with HCV infection and 92 HCV-negative Puerto Rican IDUs. We found a significant association between the presence of different combinations of KIR inhibitory receptor...

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Source

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Identifiers

PMID: 19552960
DOI: 10.1016/j.molimm.2009.05.014
PMCID: PMC2813779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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