Article
Differences in viral kinetics between genotypes 1 and 2 of hepatitis C virus after single administration of standard interferon-alpha.
Journal of medical virology - 1 Aug 2009
Toyoda Hidenori, Kumada Takashi, Kiriyama Seiki, Sone Yasuhiro, Tanikawa Makoto, Hisanaga Yasuhiro, Kanamori Akira, Atsumi Hiroyuki, Takagi Makiko, Nakano Satoshi, Arakawa Takahiro, Fujimori Masashi
Abstract excerpt
Hepatitis C virus (HCV) kinetics were determined after a single administration of standard interferon (IFN) according to the HCV genotype that affects the response to antiviral therapy with IFN/peginterferon. A total of 208 patients were investigated. All patients received a single administration of 6 megaunits of standard IFN-alpha. HCV RNA concentration was measured before, and at 24, 48, 72, and 120 hr after...
Topics
- Adult
- Aged
- Female
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Interferon-alpha
- Male
- Middle Aged
- RNA, Viral
- Time Factors
- Viral Load