Hepatitis C virus genotypes 1 and 2 respond to interferon-alpha with different virologic kinetics.

doi:10.1093/infdis/172.4.934

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Article

Hepatitis C virus genotypes 1 and 2 respond to interferon-alpha with different virologic kinetics.

The Journal of infectious diseases - 1 Oct 1995

Kohara M, Tanaka T, Tsukiyama-Kohara K, Tanaka S, Mizokami M, Lau J Y, Hattori N

Abstract excerpt

Responses of patients infected with chronic hepatitis C virus (HCV) to interferon-alpha (IFN-alpha) treatment were studied. HCV genotypes were determined by molecular and serologic techniques. Levels of HCV viremia were determined by quantitative reverse transcription-polymerase chain reaction. Infection with HCV genotype 2 or low pretreatment HCV viremia levels in subjects infected with genotype 1 were...

Topics

Adult
Aged
Alanine Transaminase
Antiviral Agents
Dose-Response Relationship, Drug
Female
Genotype
Hepacivirus
Hepatitis C
Humans
Interferon-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymerase Chain Reaction

RNA, Viral

Serotyping

Species Specificity

Source

Open in PubMed

Identifiers

PMID: 7561212
DOI: 10.1093/infdis/172.4.934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7561212-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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