Article
Twenty-four hour kinetics of hepatitis C virus and antiviral effect of alpha-interferon.
Journal of medical virology - 1 Mar 2006
Boulestin Anne, Kamar Nassim, Sandres-Sauné Karine, Legrand-Abravanel Florence, Alric Laurent, Vinel Jean-Pierre, Rostaing Lionel, Izopet Jacques
Abstract excerpt
Numerous studies reported that patients infected by the genotype 1 of hepatitis C virus (HCV) and/or with a high baseline viral load responded poorly to antiviral therapy. Study of viral kinetics has provided clues to the understanding of non-response to alpha-interferon (IFN-alpha)-based therapy. The objective of this study was to clarify the influence of viral factors such as the genotype and baseline viral...
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