Article
Hepatitis C virus genotypes and hepatic fibrosis regulate 24-h decline of serum hepatitis C virus RNA during interferon therapy in patients with chronic hepatitis C.
Journal of gastroenterology and hepatology - 1 Apr 2003
Karino Yoshiyasu, Toyota Jouji, Sugawara Masaaki, Miyazaki Kayo, Kuwata Yasuaki, Yamazaki Katsu, Sato Takahiro, Ohmura Takumi, Matsushima Takashi
Abstract excerpt
BACKGROUND AND AIMS: Recently, hepatitis C virus (HCV) dynamics during interferon (IFN) therapy have been studied in detail. We examined factors that regulate the viral kinetics and the relationship between the viral kinetics and clinical effect of IFN therapy. METHODS: Eighty-eight patients with chronic hepatitis C entered this study. All patients had been treated with 3 MU of IFN-beta twice a day for the first...
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