Article
Screening of mutations in the GCK gene in Jordanian maturity-onset diabetes of the young type 2 (MODY2) patients.
Genetics and molecular research : GMR - 5 May 2009
Khalil R, Al-Sheyab F, Khamaiseh E, Halaweh M A, Abder-Rahman H A
Abstract excerpt
Maturity-onset diabetes of the young type 2 (MODY2) is a genetic form of diabetes mellitus caused by mutations in the glucokinase gene (GCK). We assessed the frequency of GCK gene mutations in Jordanian suspected MODY2 patients. We screened exons 7, 8 and 9, which are specific for pancreatic glucokinase, for mutations at positions 682A>G, p.T228A; 895G>C, p.G299R, and 1148C>A, p.S383X, respectively, in 250...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.