Article
Inhibition of p38 MAPK facilitates ex vivo expansion of skin epithelial progenitor cells.
In vitro cellular & developmental biology. Animal - 1 Oct 2009
Peng Juan, Li Wei, Li Haibo, Jia Yanni, Liu Zuguo
Abstract excerpt
Ex vivo expansion of skin epithelial stem cells has long attracted great interest because of the potential utilization in transplantation and gene therapy. The use of cultured stem or progenitor cells was limited by the lack of applicable culturing system with both satisfactory expansion efficacy and well suppressed differentiation ex vivo. The p38 mitogen-activated protein kinase (MAPK) pathways are responsible...
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