Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A functional polymorphism in MMP1 could influence osteomyelitis development.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 2010

Montes Angel Hugo, Valle-Garay Eulalia, Alvarez Victoria, Pevida Marta, García Pérez Eva, Paz Jose, Meana Alvaro, Asensi Victor

Abstract excerpt

Osteomyelitis (OM) is a bone infection characterized by necrosis and new formation of bone. Because matrix metalloproteases (MMPs) play an important role in bone extracellular matrix remodeling, we investigated the role of some MMP polymorphisms in OM patients. A total of 118 OM patients and 300 blood donors were genotyped for the polymorphisms of MMP1 (-1607 1G/2G) and MMP13 (-77A/G). Levels of MMPs (-1, -2, -3,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interleukin-1alpha
Share to Matrix Metalloproteinase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Matrix Metalloproteinase 13

Share to Matrix Metalloproteinase 3

Share to Matrix Metalloproteinase 8

Share to Osteomyelitis

Share to Proto-Oncogene Protein c-ets-1

Share to Tissue Inhibitor of Metalloproteinases

Source

Identifiers

PMID: 19821768
DOI: 10.1359/jbmr.091013

Genes

MMP1
MMP13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A functional polymorphism in MMP1 could influence osteomyelitis development.PMID 19821768Read ↗

IL-1 alpha (-889) promoter polymorphism is a risk factor for osteomyelitis.Semantic proximity Read ↗

Examining the association of MMP-1 gene -1607 (2G/1G) and -519 (A/G) polymorphisms with the risk of osteomyelitis: A case-control study.Semantic proximity Read ↗

MMP-1 polymorphism and its relationship to pathological processes.Semantic proximity Read ↗

Single nucleotide polymorphisms in the development of osteomyelitis and prosthetic joint infection: a narrative review.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in pro-inflammatory cytokine and toll-like receptor genes with pediatric hematogenous osteomyelitis.Semantic proximity Read ↗

Variation in the matrix metalloproteinase‐3, ‐7, ‐12 and ‐13 genes is associated with functional status in rheumatoid arthritisSemantic proximity Read ↗

MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 expression in association with pro-inflammatory milieu elements.Semantic proximity Read ↗

Investigation of polymorphisms in anti-inflammatory cytokine genes in hematogenous osteomyelitis.Semantic proximity Read ↗

Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression.Semantic proximity Read ↗

A link between osteomyelitis and IL1RN and IL1B polymorphisms-a study in patients from Northeast Brazil.Semantic proximity Read ↗

Investigation of the relationship between MMP-1 (- 1607 1G/2G), MMP-3 (- 1171 5A/6A) gene variations and development of bladder cancer.Semantic proximity Read ↗

The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and haematogenous osteomyelitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.