Article
Possible association of prokineticin 2 receptor gene (PROKR2) with mood disorders in the Japanese population.
Neuromolecular medicine - 1 Jan 2009
Kishi Taro, Kitajima Tsuyoshi, Tsunoka Tomoko, Okumura Takenori, Ikeda Masashi, Okochi Tomo, Kinoshita Yoko, Kawashima Kunihiro, Yamanouchi Yoshio, Ozaki Norio, Iwata Nakao
Abstract excerpt
Several investigations have suggested that disruption of circadian rhythms may provide the foundation for the development of mood disorders such as bipolar disorder (BP) and major depressive disorder (MDD). Recent animal studies reported that prokineticin 2 or prokineticin 2 receptor gene deficient mice showed disruptions in circadian and homeostatic regulation of sleep. This evidence indicates that prokineticin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
