Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation prediction models in Lynch syndrome: evaluation in a clinical genetic setting.

Journal of medical genetics - 1 Nov 2009

Ramsoekh D, van Leerdam M E, Wagner A, Kuipers E J, Steyerberg E W

Abstract excerpt

BACKGROUND/AIMS: The identification of Lynch syndrome is hampered by the absence of specific diagnostic features and underutilisation of genetic testing. Prediction models have therefore been developed, but they have not been validated for a clinical genetic setting. The aim of the present study was to evaluate the usefulness of currently available prediction models. METHODS: The authors collected data of 321...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Area Under Curve
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to Germ-Line Mutation

Share to Predictive Value of Tests

Share to Reproducibility of Results

Share to ROC Curve

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 19541685
DOI: 10.1136/jmg.2009.066589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation prediction models in Lynch syndrome: evaluation in a clinical genetic setting.PMID 19541685Read ↗

Prediction models in Lynch syndrome.Semantic proximity Read ↗

Performance of Lynch Syndrome Predictive Models in a Multi-Center US Referral PopulationSemantic proximity Read ↗

Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer.Semantic proximity Read ↗

Predictive models for mutations in mismatch repair genes: implication for genetic counseling in developing countries.Semantic proximity Read ↗

Criteria and prediction models for mismatch repair gene mutations: a review.Semantic proximity Read ↗

A comparison of models used to predict MLH1, MSH2 and MSH6 mutation carriers.Semantic proximity Read ↗

Genetic mutation risk calculation in Lynch syndrome inheritance: Evaluating the utility of the PREMM1,2,6 model in Lyon: The first French study.Semantic proximity Read ↗

Evaluation of predictive models in daily practice for the identification of patients with Lynch syndrome.Semantic proximity Read ↗

Comparison of predictive models, clinical criteria and molecular tumour screening for the identification of patients with Lynch syndrome in a population-based cohort of colorectal cancer patientsSemantic proximity Read ↗

Prediction of Lynch syndrome in consecutive patients with colorectal cancer.Semantic proximity Read ↗

Comparative Effectiveness of Screening Strategies for Lynch SyndromeSemantic proximity Read ↗

Use and feasibility of a Lynch Syndrome predictive model for inherited colorectal and endometrial cancer in a low-middle income country.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.