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Article

A comparison of models used to predict MLH1, MSH2 and MSH6 mutation carriers.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Apr 2009

Pouchet C J, Wong N, Chong G, Sheehan M J, Schneider G, Rosen-Sheidley B, Foulkes W, Tischkowitz M

Abstract excerpt

BACKGROUND: MMRpro, prediction of mutations in MLH1 and MLH2 (PREMM(1,2)) and MMRpredict are models which were developed to predict the probability that an individual carries a Lynch syndrome-causing mutation. Each model utilizes data from personal and family histories of cancer. To date, no studies have compared these models in a cancer genetics clinic. The purpose of this study was to determine each model's...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Carrier Screening

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Share to MutL Protein Homolog 1

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Source

Identifiers

PMID: 19164453
DOI: 10.1093/annonc/mdn686

Genes

MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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