Article
Apolipoprotein-E gene variants associated with cardiovascular risk factors in antipsychotic recipients.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Oct 2009
Clark D, Skrobot O A, Adebiyi I, Susce M T, de Leon J, Blakemore Ai F, Arranz M J
Abstract excerpt
Interest exists in identifying the factors that specifically contribute to the increased prevalence of cardiovascular disease observed in psychiatric disease. The apolipoprotein-E (APOE) gene codes for a protein that has a key role in metabolism of cholesterol and triglycerides, with increased levels of apoE found in specific areas of post-mortem schizophrenic brains. This study investigated whether apoE variants...
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