Article
Comparative study of apolipoprotein-E polymorphism and plasma lipid levels in dyslipidemic and asymptomatic subjects, and their implication in cardio/cerebro-vascular disorders.
Neurochemistry international - 1 Jan 2010
Ferreira Cláudia N, Carvalho Maria G, Fernandes Ana P S M, Lima Luciana M, Loures-Valle Andréia A, Dantas Julizar, Janka Zoltán, Palotás András, Sousa Marinez O
Abstract excerpt
Polymorphisms in the apolipoprotein-E (apoE) gene may modulate lipoprotein metabolism at different steps and influence total and low density lipoprotein (LDL) cholesterol (LDLc) levels, as well as other lipid features. Population studies have documented significant differences in the frequency of apoE alleles which are related to the prevalence of various cardio-vascular and neuro-psychiatric diseases. In this...
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