Article
Diversity of apolipoprotein E genetic polymorphism significance on cardiovascular risk is determined by the presence of metabolic syndrome among hypertensive patients.
Lipids in health and disease - 20 Nov 2014
Teixeira Andrei Alkmim, Marrocos Mauro Sergio, Quinto Beata Marie Redublo, Dalboni Maria Aparecida, Rodrigues Cassio Jose de Oliveira, Carmona Silmara de Melo, Kuniyoshi Mariana, Batista Marcelo Costa
Abstract excerpt
BACKGROUND: Hypertension has a significant relevance as a cardiovascular risk factor. A consistent increase on world's Metabolic Syndrome (MetS) incidence has been associated with an epidemic cardiovascular risk in different populations. Dislipidemia plays a major role determining the epidemic CV burden attributed to MetS. Apolipoprotein E (ApoE) is involved on cholesterol and triglycerides metabolism regulation....
Topics
- Aged
- Apolipoproteins E
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Male
- Metabolic Syndrome