Article
Low prevalence of lipid metabolism abnormalities in APOE ε2-genotype and male patients 60 years or older with schizophrenia.
BMC psychiatry - 12 Dec 2017
Ban Chunxia, Zhang Qunying, Feng Jie, Li Huijuan, Qiu Qi, Tian Yuan, Li Xia
Abstract excerpt
BACKGROUND: Schizophrenia is a serious mental disorder largely manageable with atypical antipsychotics; however, these drugs have been associated with glucose/lipid metabolism issues such as diabetes and hyperlipidaemia. Apolipoprotein E (APOE) is the most abundant apolipoprotein, and APOE genotypes have been correlated with lipid metabolism phenotypes in an age-dependent manner. Studies examining the...
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