Article
Association study between genetic variants at the PIP5K2A gene locus and schizophrenia and bipolar affective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2006
Jamra Rami Abou, Klein Katrin, Villela Angela Wolf, Becker Tim, Schulze Thomas G, Schmael Christine, Deschner Monika, Klopp Norman, Illig Thomas, Propping Peter, Cichon Sven, Rietschel Marcella, Nöthen Markus M, Schumacher Johannes
Abstract excerpt
Results from molecular and pharmacological studies point to involvement of the gene coding for the phosphatidylinositol-4-phosphate 5-kinase type II-alpha (PIP5K2A) in the development of schizophrenia and bipolar affective disorder (BPAD). The PIP5K2A gene locus, which is located on chromosomal region 10p12, has been implicated in the development of both disorders by independent linkage and association studies....
Topics
- Bipolar Disorder
- Case-Control Studies
- Genetic Markers
- Genetic Variation
- Humans
- Phosphotransferases (Alcohol Group Acceptor)
- Schizophrenia