Article
Effect of rec mutations on viability and processing of DNA damaged by methylmethane sulfonate in xth nth nfo cells of Escherichia coli.
Biochemical and biophysical research communications - 31 Oct 1991
Wang T C, Chang H Y
Abstract excerpt
The role of recombination genes in the processing of DNA damaged by methlymethane sulfonate (MMS) was examined in an xth nth nfo strain of Escherichia coli K-12. Introduction of a recQ mutation did not increase the cell's sensitivity to MMS treatment. The presence of recF, recJ or recN mutation slightly increased the cell's sensitivity to MMS treatment. The introduction of recA or recB mutation into the cells led...
Topics
- DNA Damage
- DNA Repair
- DNA, Bacterial
- Escherichia coli
- Genes, Bacterial
- Genotype
- Kinetics
- Methyl Methanesulfonate
- Mutation
- Recombination, Genetic
- Transduction, Genetic