Article
Serratia marcescens rpr gene sensitizes Escherichia coli wild-type, xth, and nfo strains to methyl methanesulphonate.
Molecular microbiology - 1 Apr 1990
Murphy K E, Braymer H D
Abstract excerpt
It is reported here that the rpr DNA repair gene of Serratia marcescens does not complement an Escherichia coli xth nfo AP endonuclease mutation for resistance to methyl methanesulphonate (MMS). Rather, rpr sensitized Escherichia coli wild-type, xth, and nfo strains to MMS. Also, it was found that rpr could not complement a triple tag alkA recA mutation in E. coli, indicating that there are limits to rpr...
Topics
- DNA Glycosylases
- DNA Repair
- DNA, Bacterial
- DNA-(Apurinic or Apyrimidinic Site) Lyase
- Deoxyribonuclease IV (Phage T4-Induced)
- Drug Resistance, Microbial
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Gene Amplification