Article
The proline 12 alanine substitution in the PPARgamma2 gene is associated with increased extent of coronary artery disease in men.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Oct 2009
Schneider J G, Schiekofer S, von Eynatten M, Schlimmer P, Dugi K A
Abstract excerpt
OBJECTIVE: To determine whether there is an independent association between the Pro12Ala polymorphism in the peroxisome proliferator-activated-receptor gamma2 (PPARgamma2)-gene and the extent of coronary artery disease in men. RESEARCH DESIGN AND METHODS: We determined the Pro12Ala polymorphism in the PPARgamma2 gene in 240 male patients undergoing elective coronary angiograpy, and quantitated the degree of CAD...
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