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Article

A Pro 12 Ala substitution in the PPARγ2 polymorphism may decrease the number of diseased vessels and the severity of angiographic coronary artery.

Coronary artery disease - 1 Aug 2013

Youssef Sarraj Mohamed, Mohamed Najah, Afef Slimani, Khaldoun Ben H, Fadoua Neffati, Fadhel Najjar M, Naceur Slimane M

Abstract excerpt

AIMS: Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates the gene expression of the key proteins involved in lipid metabolism, vascular inflammation, and proliferation. PPARγ may contribute toward attenuation of atherogenesis. We investigated the relationship of the Pro 12 Ala PPARγ2 polymorphism with the presence and severity of coronary artery disease...

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Source

Identifiers

PMID: 23652363
DOI: 10.1097/MCA.0b013e328361a95e

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A Pro 12 Ala substitution in the PPARγ2 polymorphism may decrease the number of diseased vessels and the severity of angiographic coronary artery.PMID 23652363Read ↗

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