Article
Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis.
Heart (British Cardiac Society) - 1 Oct 2003
Ye S, Dhillon S, Seear R, Dunleavey L, Day L B, Bannister W, Day I N M, Simpson I
Abstract excerpt
OBJECTIVE: To test the hypothesis that gene-gene interaction of the renin-angiotensin system is associated with an effect on the extent of coronary atherosclerosis. SETTING AND RESULTS: A cohort of 1162 patients with coronary artery disease were genotyped for genetic polymorphisms in the renin-an...
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