Article
Complex segregation analysis of pedigrees from the Gilda Radner Familial Ovarian Cancer Registry reveals evidence for mendelian dominant inheritance.
PloS one - 17 Jun 2009
Tayo Bamidele O, DiCioccio Richard A, Liang Yulan, Trevisan Maurizio, Cooper Richard S, Lele Shashikant, Sucheston Lara, Piver Steven M, Odunsi Kunle
Abstract excerpt
BACKGROUND: Familial component is estimated to account for about 10% of ovarian cancer. However, the mode of inheritance of ovarian cancer remains poorly understood. The goal of this study was to investigate the inheritance model that best fits the observed transmission pattern of ovarian cancer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
