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Article

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes.

British journal of cancer - 7 Jan 2002

Antoniou A C, Pharoah P D P, McMullan G, Day N E, Stratton M R, Peto J, Ponder B J, Easton D F

Abstract excerpt

In computing the probability that a woman is a BRCA1 or BRCA2 carrier for genetic counselling purposes, it is important to allow for the fact that other breast cancer susceptibility genes may exist. We used data from both a population based series of breast cancer cases and high risk families in the UK, with information on BRCA1 and BRCA2 mutation status, to investigate the genetic models that can best explain...

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Source

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Identifiers

PMID: 11857015
DOI: 10.1038/sj.bjc.6600008
PMCID: PMC2746531

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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