Article
The genetics of ovarian cancer.
Best practice & research. Clinical obstetrics & gynaecology - 1 Aug 2002
Pharoah Paul D P, Ponder Bruce A J
Abstract excerpt
A family history of ovarian cancer confers an increased risk of ovarian cancer. We review the literature quantifying the familial risks associated with ovarian cancer and assess the evidence that the familial clustering of ovarian cancer is genetically determined. We then describe the known high-penetrance genes, the ovarian cancer risks attached to them and their contribution to ovarian cancer in families and in...
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