Article
Complex patterns of Hepatitis-C virus longitudinal clustering in a high-risk population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2018
Rose Rebecca, Lamers Susanna L, Massaccesi Guido, Osburn William, Ray Stuart C, Thomas David L, Cox Andrea L, Laeyendecker Oliver
Abstract excerpt
We investigated longitudinal viral clustering among and within subjects in a highly networked cohort of people who inject drugs (PWID). All subjects had estimated dates of infection and two or more E1 sequences (bp 943-1288 relative to H77) with 1 to 14years of follow up. Two methods (HIV-TRACE and PhyloPart) were used to determine clusters. Genetic distance thresholds were determined by comparing intra-and...
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