Article
Development of a new genotyping assay for detection of the BDNF Val66Met polymorphism using melting-curve analysis.
Pharmacogenomics - 1 Jun 2009
Sánchez-Romero María Antonia, Dorado Pedro, Guarino Estrella, Llerena Adrián
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) plays a critical role in the growth, differentiation and survival of neurons in the CNS. Recent research has suggested that BDNF may be implicated in the etiology of mood disorders and schizophrenia, as well as in the therapeutic action of some drugs, such as antidepressants and antipsychotics. This study aimed to develop a simple, fast and accurate new method for...
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