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Article

Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats.

The Journal of pharmacology and experimental therapeutics - 1 Sept 2009

Sun Cheuk-Kwan, Lee Fan-Yen, Sheu Jiunn-Jye, Yuen Chun-Man, Chua Sarah, Chung Sheng-Ying, Chai Han-Tan, Chen Yen-Ta, Kao Ying-Hsien, Chang Li-Teh, Yip Hon-Kan

Abstract excerpt

We investigated whether early combined cilostazol and bone marrow-derived endothelial progenitor cell (BMDEPC) treatment offers synergistic benefit in ameliorating monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) in rats. Male Sprague-Dawley rats (n = 10/group) were randomized to receive saline injection only (group 1), MCT (70 mg/kg) (group 2), and MCT plus cilostazol (20 mg/kg/day) (group 3),...

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PMID: 19528354
DOI: 10.1124/jpet.109.154328

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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