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Article

Intratracheal transplantation of endothelial progenitor cells attenuates smoking-induced COPD in mice.

International journal of chronic obstructive pulmonary disease - 1 Jan 2017

Shi Zhihui, Chen Yan, Cao Jun, Zeng Huihui, Yang Yue, Chen Ping, Luo Hong, Peng Hong, Cai Shan, Guan Chaxiang

Abstract excerpt

BACKGROUND: Endothelial progenitor cells (EPCs) might play a protective role in COPD. The aim of this study was to investigate whether intratracheal allogeneic transplantation of bone-marrow-derived EPCs would attenuate the development of smoking-induced COPD in mice. METHODS: Isolated mononuclear cells from the bone marrow of C57BL/6J mice were cultured in endothelial cell growth medium-2 for 10 days, yielding...

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Identifiers

PMID: 28360519
DOI: 10.2147/COPD.S110781
PMCID: PMC5365327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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