Article
Molecular genetics of the Posterior sex combs/Suppressor 2 of zeste region of Drosophila: aberrant expression of the Suppressor 2 of zeste gene results in abnormal bristle development.
Genetics - 1 May 1991
Brunk B P, Martin E C, Adler P N
Abstract excerpt
We report the molecular characterization of the Posterior sex combs-Suppressor 2 of zeste region of Drosophila melanogaster. The distal breakpoint of the Aristapedioid inversion divides the region into two parts. We have molecularly mapped the lesions associated with several loss of function mutations in the Polycomb group gene Posterior sex combs (Psc) proximal to this breakpoint. In addition, we have found that...
Topics
- Animals
- Blotting, Northern
- Chromosome Deletion
- DNA
- Drosophila melanogaster
- Genes, Suppressor
- Mutation
- Nucleic Acid Hybridization
- Phenotype
- Restriction Mapping
- Transcription, Genetic