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Article

Rank-based inverse normal transformations are increasingly used, but are they merited?

Behavior genetics - 1 Sept 2009

Beasley T Mark, Erickson Stephen, Allison David B

Abstract excerpt

Many complex traits studied in genetics have markedly non-normal distributions. This often implies that the assumption of normally distributed residuals has been violated. Recently, inverse normal transformations (INTs) have gained popularity among genetics researchers and are implemented as an option in several software packages. Despite this increasing use, we are unaware of extensive simulations or...

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PMID: 19526352
DOI: 10.1007/s10519-009-9281-0
PMCID: PMC2921808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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