Article
The use of resolvases T4 endonuclease VII and T7 endonuclease I in mutation detection.
Molecular biotechnology - 1 Jan 2003
Babon J J, McKenzie M, Cotton R G H
Abstract excerpt
Mutation and polymorphism detection is of increasing importance in the field of molecular genetics. This is reflected by the plethora of chemical, enzymatic, and physically based methods of mutation detection. The ideal method would detect mutations in large fragments of DNA and position them to single base-pair (bp) accuracy. Few methods are able to quickly screen kilobase lengths of DNA and position the...
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