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Article

Use of mouse models to understand the molecular basis of tissue-specific tumorigenesis in the Carney complex.

Journal of internal medicine - 1 Jul 2009

Kirschner L S

Abstract excerpt

Carney complex (CNC) is an autosomal dominant, multiple endocrine neoplasia syndrome comprised of spotty skin pigmentation, myxomatosis, endocrine tumours and schwannomas. The majority of cases are due to inactivating mutations in PRKAR1A, the gene encoding the type 1A regulatory subunit of the 3',5'-cyclic adenosine monophosphate (cAMP)-dependent protein kinase, PKA (protein kinase A). In order to understand the...

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Identifiers

PMID: 19522826
DOI: 10.1111/j.1365-2796.2009.02114.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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