Article
Syntaxin specificity of aquaporins in the inner medullary collecting duct.
American journal of physiology. Renal physiology - 1 Aug 2009
Mistry Abinash C, Mallick Rickta, Klein Janet D, Weimbs Thomas, Sands Jeff M, Fröhlich Otto
Abstract excerpt
Proper targeting of the aquaporin-2 (AQP2) water channel to the collecting duct apical plasma membrane is critical for the urine concentrating mechanism and body water homeostasis. However, the trafficking mechanisms that recruit AQP2 to the plasma membrane are still unclear. Snapin is emerging as an important mediator in the initial interaction of trafficked proteins with target soluble...
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