Article
Signals of major histocompatibility complex overdominance in a wild salmonid population.
Proceedings. Biological sciences - 7 Sept 2009
Kekäläinen Jukka, Vallunen J Albert, Primmer Craig R, Rättyä Jouni, Taskinen Jouni
Abstract excerpt
The major histocompatibility complex (MHC) contains the most variable genes in vertebrates, but despite extensive research, the mechanisms maintaining this polymorphism are still unresolved. One hypothesis is that MHC polymorphism is a result of balancing selection operating by overdominance, but convincing evidence for overdominant selection in natural populations has been lacking. We present strong evidence...
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