Article
MHC class IIB alleles contribute to both additive and nonadditive genetic effects on survival in Chinook salmon.
Molecular ecology - 1 Aug 2006
Pitcher Trevor E, Neff Bryan D
Abstract excerpt
The genes of the major histocompatibility complex (MHC) are found in all vertebrates and are an important component of individual fitness through their role in disease and pathogen resistance. These genes are among the most polymorphic in genomes and the mechanism that maintains the diversity has been actively debated with arguments for natural selection centering on either additive or nonadditive genetic...
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