Epidemiological features of Wegener's granulomatosis and microscopic polyangiitis: two diseases or one 'anti-neutrophil cytoplasm antibodies-associated vasculitis' entity?

Abstract excerpt

Because of their multiple overlapping clinical characteristics, Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) have increasingly been conceptualized as different expressions of a unique anti-neutrophil cytoplasm antibodies (ANCA)-associated vasculitis (AAV) disease spectrum. However, this continuum theory remains hindered by uncertainty surrounding a potentially common etiology. This review...

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