Article
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment.
Autoimmunity reviews - 1 Nov 2014
Comarmond Cloé, Cacoub Patrice
Abstract excerpt
Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis, which affects small- and medium-sized blood vessels and is often associated with cytoplasmic ANCA. GPA occurs in patients between 45 and 60 years old of both genders, and is rarely observed in blacks. The prevalence of GPA increases along a south-north gradient in Europe (20 to 150/million). The main clinical characteristics involve the...
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