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Article

A Cohort Study of STMN1 Expression in Colorectal Cancer: Body Mass Index and Prognosis

9 Jun 2009

Abstract excerpt

OBJECTIVES: STMN1 (stathmin or oncoprotein-18) destabilizes microtubules and reorganizes cytoskeleton, and functions in cell cycle progression and cell migration. STMN1 activity is influenced by p53, p27, and the PI3K/AKT pathway. However, its prognostic significance in colon cancer is uncertain. METHODS: Utilizing 546 colorectal cancers (stage I-IV) from two independent prospective cohort studies (the Nurses'...

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PMID: 19513025
DOI: 10.1038/ajg.2009.281

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