Article
Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2016
McCleary Nadine J, Sato Kaori, Nishihara Reiko, Inamura Kentaro, Morikawa Teppei, Zhang Xuehong, Wu Kana, Yamauchi Mai, Kim Sun A, Sukawa Yasutaka, Mima Kosuke, Qian Zhi Rong, Fuchs Charles S, Ogino Shuji, Meyerhardt Jeffrey A
Abstract excerpt
PURPOSE: We hypothesized that adverse prognostic associations of specific tumor molecular factors vary by patient age at colorectal cancer diagnosis. EXPERIMENTAL DESIGN: We examined the prognostic associations and interactions by age at colorectal cancer diagnosis (<60 vs. 60-74 vs. ≥75 years ol...
Topics
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Case-Control Studies
- Colorectal Neoplasms
- Comorbidity
- CpG Islands
- DNA Methylation
- Female
- Gene Expression Profiling
- Humans