Searching for the 'X' factor: investigating the genetics of primary ovarian insufficiency.

Abstract excerpt

Primary ovarian insufficiency (POI) is the cessation of ovarian function before the age of 40. The causes of POI are heterogeneous, but substantial evidence exists to support a genetic basis of POI, particularly in the critical involvement of genes on the X chromosome. Recent studies have revealed novel candidate genes through the identification of copy number variations associated with POI. This review...

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• Share to Chromosomes, Human, X
• Share to DNA Copy Number Variations
• Share to Genes, X-Linked