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Article

Association of 8q22.3 locus in Chinese Han with idiopathic premature ovarian failure (POF).

Human molecular genetics - 15 Jan 2012

Qin Yingying, Zhao Han, Xu Jianfeng, Shi Yongyong, Li Zhiqiang, Qiao Jie, Liu Jiayin, Qin Chunrong, Ren Chune, Li Jie, Chen Shiling, Cao Yunxia, Simpson Joe Leigh, Chen Zi-Jiang

Abstract excerpt

Premature ovarian failure (POF) is a complex heritable disorder known to be caused by chromosomal abnormalities and to date a limited number of known mutations, often autosomal. We sought to identify additional genetic loci associated with POF by performing the first large-scale genome-wide association study (GWAS). GWAS, using Affymetrix SNP 6.0 chip, was conducted in an initial discovery set of 391...

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Identifiers

PMID: 21989058
DOI: 10.1093/hmg/ddr462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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