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Article

Identification of potential causal variants for premature ovarian failure by whole exome sequencing.

BMC medical genomics - 27 Oct 2020

Jin Haengun, Ahn JuWon, Park YoungJoon, Sim JeongMin, Park Han Sung, Ryu Chang Soo, Kim Nam Keun, Kwack KyuBum

Abstract excerpt

BACKGROUND: Premature ovarian failure (POF) is a highly heterogeneous disorder that occurs in 1% of women of reproductive age. Very few causative genes and variants contributing to POF have been detected, and the disease remains incompletely understood. In this study, we used whole exome sequencing (WES) to identify potential causal variants leading to POF. METHODS: WES was conducted to identify variants in 34...

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Identifiers

PMID: 33109206
DOI: 10.1186/s12920-020-00813-x
PMCID: PMC7590468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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